Sau đây là danh sách các thành phố chính tại Vùng Đại Los Angeles với dân số ước tính năm 2005 theo Cục điều tra dân số Hoa Kỳ:

• Los Angeles—Long Beach—Santa Ana MSA
  • Los Angeles, California (3.849.378)
  • Long Beach, California (472.494)
  • Santa Ana, California (340.024)
  • Anaheim, California (334.425)
  • Glendale, California (199.463)
  • Huntington Beach, California (194.436)
  • Irvine, California (193.956)
  • Pomona, California (154.271)
  • Pasadena, California (144.133)
  • Torrance, California (142.350)
  • Orange, California (135.070)
  • Fullerton, California (132.918)
  • Costa Mesa, California (109.809)
  • Burbank, California (104.317)
  • Compton, California (95.701)
  • Carson, California (93.805)
  • Westminster, California (88.207)
  • Santa Monica, California (88.050)
  • Newport Beach, California (80.006)
  • Tustin, California (69.665)
  • Montebello, California (62.968)
  • Monterey Park, California (62.183)
  • Gardena, California (59.733)
  • Arcadia, California (56.486)
  • Paramount, California (56.369)
  • Fountain Valley, California (55.857)
  • Cerritos, California (52.353)
• Riverside—San Bernardino—Ontario MSA
  • Riverside, California (293.761)
  • San Bernardino, California (198.985)
  • Moreno Valley, California (180.466)
  • Ontario, California (173.351)
  • Victorville, California (98.662)
  • Temecula, California (89.392)
  • Chino, California (79.289)
  • Redlands, California (70.382)
  • Hemet, California (70.136)
  • Colton, California (51.427)
• Oxnard—Thousand Oaks—Ventura MSA
  • Oxnard, California (184.463)
  • Thousand Oaks, California (124.207)
  • Simi Valley, California (112.345)
  • Ventura, California (104.092)
  • Camarillo, California (62.489)